Creuse is a 255 km long river in western France. Its source is in the north-western Massif Central. It flows north-west through the following départements and cities:

• Creuse (named after the river): Aubusson.
• Indre: Argenton-sur-Creuse , Le Blanc.
• Indre-et-Loire.
• Vienne: La Roche-Posay

The Creuse flows into the river Vienne about 20 km north of Châtellerault. A tributary of the river Creuse is the Gartempe.